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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CCDC134 Antibody (C-term)   

CCDC134 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CCDC134 Antibody (C-term) AP13242b
    CCDC134 Antibody (C-term) (Cat. #AP13242b) western blot analysis in HepG2,CEM cell line lysates (35ug/lane).This demonstrates the CCDC134 antibody detected the CCDC134 protein (arrow).
  • IHC-P - CCDC134 Antibody (C-term) AP13242b
    CCDC134 Antibody (C-term) (Cat. #AP13242b)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCDC134 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H6E4
Other Accession Q5M862, NP_079097.1
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 26561 Da
Antigen Region 197-225 aa
Additional Information
Gene ID 79879
Other Names Coiled-coil domain-containing protein 134, CCDC134
Target/Specificity This CCDC134 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human CCDC134.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCDC134 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCDC134
Function In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function (PubMed:25125657). Enhances cytotoxic anti-tumor activity of CD8(+) T cells (PubMed:25125657). May inhibit ERK and JNK signaling activity (PubMed:18087676, PubMed:23070808). May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling (PubMed:23070808).
Cellular Location Nucleus. Cytoplasm. Secreted. Endoplasmic reticulum. Note=Accumulates in the nucleus in response to UV irradiation (PubMed:22644376)
Tissue Location Expressed in cervical gland, cervical squamous epithelium, endometrium, stomach, kidney distal convoluted tubule, spermatogenic cells in testis, mammary gland, liver and striated muscle (at protein level) (PubMed:18087676, PubMed:23070808). Also detected in placenta (PubMed:18087676). Highest expression in testis relative to other tissues (PubMed:18087676). Detected in T cells and dendritic cells; highly expressed in activated CD8(+) T cells, and also expressed at lower levels in CD4(+) T cells (PubMed:25125657).
Research Areas
Citations (0)

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The specific function of this protein remains unknown.


Huang, J., et al. Cell. Mol. Life Sci. 65(2):338-349(2008)
Lim, J., et al. Cell 125(4):801-814(2006)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Dunham, I., et al. Nature 402(6761):489-495(1999)

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$ 295.00
$ 99.00
Cat# AP13242b
(40 western blots)
Availability: In Stock
Bulk Size
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