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ASB4 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ASB4 Antibody (C-term) AP13246b
    ASB4 Antibody (C-term) (Cat. #AP13246b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the ASB4 antibody detected the ASB4 protein (arrow).
  • IHC-P - ASB4 Antibody (C-term) AP13246b
    ASB4 Antibody (C-term) (Cat. #AP13246b)immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ASB4 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y574
Other Accession NP_057200.1, NP_665879.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48195 Da
Antigen Region 226-255 aa
Additional Information
Gene ID 51666
Other Names Ankyrin repeat and SOCS box protein 4, ASB-4, ASB4
Target/Specificity This ASB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-255 amino acids from the C-terminal region of human ASB4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsASB4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASB4
Function Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism (By similarity).
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.


Li, J.Y., et al. J. Neuroendocrinol. 17(6):394-404(2005)
Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002)
Kile, B.T., et al. Gene 258 (1-2), 31-41 (2000) :

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$ 295.00
$ 99.00
Cat# AP13246b
(40 western blots)
Availability: In Stock
Bulk Size
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