|Application ||WB, E|
|Calculated MW||49776 Da|
|Antigen Region||34-62 aa|
|Other Names||Tubulin beta-8 chain, TUBB8|
|Target/Specificity||This TUBB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-62 amino acids from the N-terminal region of human TUBB8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TUBB8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). TUBB8 has a key role in meiotic spindle assembly and oocyte maturation (PubMed:26789871).|
|Cellular Location||Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle|
|Tissue Location||Expressed at a high level in oocytes, at different stages of development.|
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Provided below are standard protocols that you may find useful for product applications.
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain (By similarity).
van Geel, M., et al. Am. J. Hum. Genet. 70(1):269-278(2002)
van Geel, M., et al. Cytogenet. Cell Genet. 88 (3-4), 316-321 (2000) :
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