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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   TFAP2B Antibody (C-term)   

TFAP2B Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TFAP2B Antibody (C-term) AP13256b
    TFAP2B Antibody (C-term) (Cat. #AP13256b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TFAP2B antibody detected the TFAP2B protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92481
Other Accession Q61313, NP_003212.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 50474 Da
Antigen Region 431-462 aa
Additional Information
Gene ID 7021
Other Names Transcription factor AP-2-beta, AP2-beta, Activating enhancer-binding protein 2-beta, TFAP2B
Target/Specificity This TFAP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-462 amino acids from the C-terminal region of human TFAP2B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTFAP2B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq].


Li, X., et al. Genes Chromosomes Cancer 49(9):819-830(2010)
Hotta, K., et al. J. Hum. Genet. (2010) In press :
Ugi, S., et al. Obesity (Silver Spring) 18(7):1277-1282(2010)
Nordquist, N., et al. Brain Res. 1305 SUPPL, S20-S26 (2009) :
Lindgren, C.M., et al. PLoS Genet. 5 (6), E1000508 (2009) :

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$ 295.00
$ 99.00
Cat# AP13256b
(40 western blots)
Availability: In Stock
Bulk Size
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