|Application ||WB, IHC-P, E|
|Calculated MW||34389 Da|
|Antigen Region||70-98 aa|
|Other Names||7-methylguanosine phosphate-specific 5'-nucleotidase, 7-methylguanosine nucleotidase, Cytosolic 5'-nucleotidase 3B, Cytosolic 5'-nucleotidase III-like protein, cN-III-like protein, N(7)-methylguanylate 5'-phosphatase, NT5C3B, NT5C3L|
|Target/Specificity||This NT5C3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human NT5C3L.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NT5C3L Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).|
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Provided below are standard protocols that you may find useful for product applications.
NT5C3L can act both as nucleotidase and as phosphotransferase (By similarity).
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