|Application ||WB, E|
|Calculated MW||153103 Da|
|Antigen Region||819-847 aa|
|Other Names||Phosphoinositide 3-kinase regulatory subunit 4, PI3-kinase regulatory subunit 4, PI3-kinase p150 subunit, Phosphoinositide 3-kinase adaptor protein, PIK3R4|
|Target/Specificity||This PIK3R4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 819-847 amino acids from the Central region of human PIK3R4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PIK3R4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory subunit of the PI3K complex. May regulate membrane trafficking late in the endocytic pathway.|
|Cellular Location||Late endosome. Note=Localizes also to discrete punctae along the ciliary axoneme|
|Tissue Location||Ubiquitously expressed.|
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Provided below are standard protocols that you may find useful for product applications.
Regulatory subunit of the PI3K complex. May regulate membrane trafficking late in the endocytic pathway.
Matsunaga, K., et al. Nat. Cell Biol. 11(4):385-396(2009)
Yan, Y., et al. Biochem. J. 417(3):747-755(2009)
Jin, J., et al. Curr. Biol. 14(16):1436-1450(2004)
Takeshita, F., et al. Semin. Immunol. 16(1):17-22(2004)
Ligon, L.A., et al. Mol. Biol. Cell 14(4):1405-1417(2003)
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