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NLE1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NVX2 |
| Other Accession | NP_060566.2, NP_001014445.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 53320 Da |
| Antigen Region | 343-372 aa |
| Gene ID | 54475 |
|---|---|
| Other Names | Notchless protein homolog 1, NLE1 |
| Target/Specificity | This NLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the C-terminal region of human NLE1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NLE1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NLE1 |
|---|---|
| Function | Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity). |
| Cellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|Ref.5} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
NLE1 (Notchless protein homolog 1) contains 8 WD repeats and may be involved in the Notch signaling pathway.
References
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)
Stanchi, F., et al. Yeast 18(1):69-80(2001)
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