PI15 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | O43692 |
Other Accession | NP_056970.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 29065 Da |
Antigen Region | 34-63 aa |
Gene ID | 51050 |
---|---|
Other Names | Peptidase inhibitor 15, PI-15, 25 kDa trypsin inhibitor, p25TI, Cysteine-rich secretory protein 8, CRISP-8, SugarCrisp, PI15, CRISP8, P25TI |
Target/Specificity | This PI15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human PI15. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PI15 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PI15 |
---|---|
Synonyms | CRISP8, P25TI |
Function | Serine protease inhibitor which displays weak inhibitory activity against trypsin (PubMed:8882727). May play a role in facial patterning during embryonic development (By similarity). |
Cellular Location | Secreted. |
Tissue Location | Weakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a trypsin inhibitor. The protein shares similarity to insect venom allergens, mammalian testis-specific proteins and plant pathogenesis-related proteins. It is frequently expressed in human neuroblastoma and glioblastoma cell lines, and thus may play a role in the central nervous system. [provided by RefSeq].
References
Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :
Kaplan, F., et al. Am. J. Physiol. 276 (6 PT 1), L1027-L1036 (1999) :
Yamakawa, T., et al. Biochim. Biophys. Acta 1395(2):202-208(1998)
Yamakawa, T., et al. Biochim. Biophys. Acta 1395(2):202-208(1998)
Koshikawa, N., et al. J. Biochem. 119(2):334-339(1996)
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