|Application ||WB, E|
|Other Accession||NP_001156793.1, NP_001156794.1, NP_296375.1, NP_001156795.1|
|Calculated MW||67567 Da|
|Antigen Region||59-88 aa|
|Other Names||Coiled-coil domain-containing protein 120, CCDC120|
|Target/Specificity||This CCDC120 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the N-terminal region of human CCDC120.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CCDC120 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for neurite growth. Localizes CYTH2 to vesicles to allow its transport along neurites, and subsequent ARF6 activation and neurite growth.|
|Cellular Location||Cytoplasm. Cell projection. Cell projection, growth cone. Endosome. Note=In differentiating neuroblastoma cells, colocalizes with CYTH2 in both neurite shaft and growth cone areas. Partially colocalizes with endosomes along neurites in differentiating neuroblastoma cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that contains a coiled-coil domain. Four alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
Tarpey, P.S., et al. Nat. Genet. 41(5):535-543(2009)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
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