|Application ||WB, IHC-P, E|
|Other Accession||Q95KB0, Q5ZIJ8, Q32LA4, NP_659489.1|
|Predicted||Bovine, Chicken, Monkey|
|Calculated MW||33786 Da|
|Antigen Region||204-233 aa|
|Other Names||Uracil phosphoribosyltransferase homolog, UPRT|
|Target/Specificity||This UPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-233 amino acids from the C-terminal region of human UPRT.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||UPRT Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.
Zhao, F.J., et al. Prostate Cancer Prostatic Dis. 12(2):166-171(2009)
Li, J., et al. J. Hum. Genet. 52(5):415-422(2007)
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