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SRP68 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP13379c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13379c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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SRP68 Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | Q9UHB9 |
| Other Accession | Q8BMA6, NP_055045.2 |
| Reactivity | Human |
| Predicted | Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 70730 Da |
SRP68 Antibody (Center) - Additional info | |
| Gene ID 6730 | |
| Other Names SRP68; Signal recognition particle 68 kDa protein | |
| Target/Specificity This SRP68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-364 amino acids from the Central region of human SRP68. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions SRP68 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
SRP68 Antibody (Center) - Protein Information | |
| Name SRP68 | |
| Function Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function | |
| Cellular Location Cytoplasm. Nucleus, nucleolus. | |
SRP68 Antibody (Center) - Related products
SRP68 Antibody (Center) - Application data
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SRP68 Antibody (Center) (Cat. #AP13379c) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the SRP68 antibody detected the SRP68 protein (arrow).
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SRP68 Antibody (Center) (Cat. #AP13379c)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SRP68 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
SRP68 Antibody (Center) - Research Areas
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BACKGROUND
The signal recognition particle (SRP) is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. This gene encodes the 68kDa component of the SRP. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq].
REFERENCES
Yoshida, M., et al. Mol. Pharmacol. 73(3):987-994(2008) Rikova, K., et al. Cell 131(6):1190-1203(2007) Menichelli, E., et al. J. Mol. Biol. 367(1):187-203(2007) Iakhiaeva, E., et al. Protein Sci. 15(6):1290-1302(2006) Fortna, A., et al. PLoS Biol. 2 (7), E207 (2004) :
