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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   BNIP2 Antibody (C-term)   

BNIP2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - BNIP2 Antibody (C-term) AP13384b
    BNIP2 Antibody (C-term) (Cat. #AP13384b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BNIP2 antibody detected the BNIP2 protein (arrow).
  • IHC-P - BNIP2 Antibody (C-term) AP13384b
    BNIP2 Antibody (C-term) (Cat. #AP13384b)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BNIP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q12982
Other Accession NP_004321.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36018 Da
Antigen Region 285-316 aa
Additional Information
Gene ID 663
Other Names BCL2/adenovirus E1B 19 kDa protein-interacting protein 2, BNIP2, NIP2
Target/Specificity This BNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-316 amino acids from the C-terminal region of human BNIP2.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBNIP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BNIP2
Synonyms NIP2
Function Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.
Cellular Location Cytoplasm. Cytoplasm, perinuclear region. Note=Localizes to the nuclear envelope region and to other cytoplasmic structures
Research Areas
Citations (0)

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Background

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. Though the specific function is unknown, it interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector.

References

Scott, G.B., et al. Biochem. J. 431(3):423-431(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Valencia, C.A., et al. Biochem. Biophys. Res. Commun. 364(3):495-501(2007)
Zhou, Y.T., et al. Exp. Cell Res. 303(2):263-274(2005)
Shang, X., et al. J. Biol. Chem. 278(46):45903-45914(2003)

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$ 295.00
$ 99.00
Cat# AP13384b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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