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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Thioredoxin 2 (Trx2) Antibody (N-term)   

Thioredoxin 2 (Trx2) Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Thioredoxin 2 (Trx2) Antibody (N-term) AP1338A
    Western blot analysis of anti-TrX Pab (Cat. #AP1338a) in mouse liver tissue lysate (35ug/lane). Trx2(arrow) was detected using the purified Pab.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q99757
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 18383 Da
Antigen Region 2-36 aa
Additional Information
Gene ID 25828
Other Names Thioredoxin, mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2
Target/Specificity This Thioredoxin 2 (Trx2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-36 amino acids from the N-terminal region of human Thioredoxin 2 (Trx2).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsThioredoxin 2 (Trx2) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TXN2
Synonyms TRX2
Function Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.
Cellular Location Mitochondrion
Tissue Location Widely expressed in adult (at protein level) and fetal tissues.
Research Areas
Citations (0)

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Background

TRX2 is a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.

References

J. Biol. Chem. 277 (36), 33249-33257 (2002)
J. Biol. Chem. 277 (36), 33242-33248 (2002)

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Discontinued
Cat# AP1338A
Size:
(40 western blots)
Alternative Products:

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