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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   DUOXA2 Antibody (C-term)   

DUOXA2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DUOXA2 Antibody (C-term) AP13417b
    DUOXA2 Antibody (C-term) (Cat. #AP13417b) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the DUOXA2 antibody detected the DUOXA2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q1HG44
Other Accession NP_997464.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34787 Da
Antigen Region 286-314 aa
Additional Information
Gene ID 405753
Other Names Dual oxidase maturation factor 2, Dual oxidase activator 2, DUOXA2
Target/Specificity This DUOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-314 amino acids from the C-terminal region of human DUOXA2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDUOXA2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Specifically expressed in thyroid. Also detected in salivary glands.
Research Areas
Citations (0)

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This gene encodes an endoplasmic reticulum protein that is necessary for proper cellular localization and maturation of functional dual oxidase 2. Mutations in this gene have been associated with thyroid dyshormonogenesis 5.


Luxen, S., et al. J. Cell. Sci. 122 (PT 8), 1238-1247 (2009) :
Zamproni, I., et al. J. Clin. Endocrinol. Metab. 93(2):605-610(2008)
Eriksson, A., et al. BMC Gastroenterol 8, 34 (2008) :
Grasberger, H., et al. Mol. Endocrinol. 21(6):1408-1421(2007)
Grasberger, H., et al. J. Biol. Chem. 281(27):18269-18272(2006)

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Cat# AP13417b
(40 western blots)
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