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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CD1C Antibody (C-term)   

CD1C Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CD1C Antibody (C-term) AP13430b
    CD1C Antibody (C-term) (Cat. #AP13430b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD1C antibody detected the CD1C protein (arrow).
  • WB - CD1C Antibody (C-term) AP13430b
    Western blot analysis of CD1C (arrow) using rabbit polyclonal CD1C Antibody (C-term) (Cat. #AP13430b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD1C gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P29017
Other Accession NP_001756.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37654 Da
Antigen Region 226-253 aa
Additional Information
Gene ID 911
Other Names T-cell surface glycoprotein CD1c, CD1c, CD1C
Target/Specificity This CD1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the C-terminal region of human CD1C.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD1C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD1C
Function Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Cellular Location Cell membrane; Single-pass type I membrane protein. Endosome membrane. Note=Subject to intracellular trafficking between the cell membrane and endosomes
Tissue Location Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues
Research Areas
Citations (0)

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This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.


Van Brussel, I., et al. J. Immunol. Methods 362 (1-2), 168-175 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Garzon, D., et al. Mol. Immunol. 47 (2-3), 253-260 (2009) :
Van Rhijn, I., et al. J. Exp. Med. 206(6):1409-1422(2009)
Kaser, A., et al. Eur. J. Immunol. 38(8):2351-2359(2008)

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$ 295.00
$ 99.00
Cat# AP13430b
(40 western blots)
Availability: In Stock
Bulk Size
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