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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   OGDH Antibody (C-term)   

OGDH Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - OGDH Antibody (C-term) AP13442b
    OGDH Antibody (C-term) (Cat. #AP13442b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the OGDH antibody detected the OGDH protein (arrow).
  • IHC-P - OGDH Antibody (C-term) AP13442b
    OGDH Antibody (C-term) (Cat. #AP13442b)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OGDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02218
Other Accession NP_002532.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 115935 Da
Antigen Region 381-410 aa
Additional Information
Gene ID 4967
Other Names 2-oxoglutarate dehydrogenase, mitochondrial, 2-oxoglutarate dehydrogenase complex component E1, OGDC-E1, Alpha-ketoglutarate dehydrogenase, OGDH
Target/Specificity This OGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-410 amino acids from the C-terminal region of human OGDH.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOGDH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
Cellular Location Mitochondrion matrix.
Research Areas
Citations (0)

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This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.


van Bever, Y., et al. Am. J. Med. Genet. A 143(7):763-767(2007)
Shi, Q., et al. J. Biol. Chem. 280(12):10888-10896(2005)
Habelhah, H., et al. J. Biol. Chem. 279(51):53782-53788(2004)
McCartney, R.G., et al. J. Biol. Chem. 273(37):24158-24164(1998)
Koike, K. Gene 159(2):261-266(1995)

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$ 295.00
$ 99.00
Cat# AP13442b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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