|Application ||WB, IF, E|
|Calculated MW||178479 Da|
|Antigen Region||721-750 aa|
|Other Names||Nik-related protein kinase, NRK|
|Target/Specificity||This NRK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 721-750 amino acids from the Central region of human NRK.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NRK Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Nakano, K., et al. Exp. Cell Res. 287(2):219-227(2003)
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