|Application ||WB, IHC-P, E|
|Other Accession||Q58DS9, NP_004574.2, NP_958842.1|
|Calculated MW||23483 Da|
|Antigen Region||178-207 aa|
|Other Names||Ras-related protein Rab-5C, L1880, RAB5L, RAB5C, RABL|
|Target/Specificity||This RAB5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the C-terminal region of human RAB5C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB5C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein transport. Probably involved in vesicular traffic (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
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Provided below are standard protocols that you may find useful for product applications.
Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Chi, A., et al. J. Proteome Res. 5(11):3135-3144(2006)
Merithew, E., et al. J. Biol. Chem. 278(10):8494-8500(2003)
Clemens, D.L., et al. Infect. Immun. 68(5):2671-2684(2000)
Bucci, C., et al. Biochem. Biophys. Res. Commun. 258(3):657-662(1999)
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