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DCTN4 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DCTN4 Antibody (N-term) AP13454A
    DCTN4 Antibody (N-term) (Cat. #AP13454a) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the DCTN4 antibody detected the DCTN4 protein (arrow).
  • IHC-P - DCTN4 Antibody (N-term) AP13454A
    DCTN4 Antibody (N-term) (Cat. #AP13454a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DCTN4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UJW0
Other Accession Q9QUR2, Q8CBY8, NP_057305.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 52337 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 51164
Other Names Dynactin subunit 4, Dyn4, Dynactin subunit p62, DCTN4
Target/Specificity This DCTN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DCTN4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDCTN4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCTN4
Function Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In skeletal muscles, demonstrates a punctate distribution along costameres (By similarity). Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization or the integrity of the Golgi but does cause both cytosolic and nuclear distribution, suggesting that this polypeptide may be targeted to the nucleus at very high expression levels.
Research Areas
Citations (0)

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DCTN4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.


Ayalon, G., et al. Cell 135(7):1189-1200(2008)
Lim, C.M., et al. J. Biol. Chem. 281(20):14006-14014(2006)
Boultwood, J., et al. Genomics 66(1):26-34(2000)
Karki, S., et al. J. Biol. Chem. 275(7):4834-4839(2000)
Bingham, J.B., et al. Curr. Biol. 9(4):223-226(1999)

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$ 295.00
$ 99.00
Cat# AP13454A
(40 western blots)
Availability: In Stock
Bulk Size
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