|Application ||WB, IHC-P, E|
|Other Accession||NP_079036.1, NP_001137458.1|
|Calculated MW||63473 Da|
|Antigen Region||30-58 aa|
|Other Names||Transducin-like enhancer protein 6, TLE6|
|Target/Specificity||This TLE6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human TLE6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TLE6 Antibody (N-term ) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.|
|Cellular Location||Cytoplasm. Note=In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity).
Chen, P.C., et al. PLoS Genet. 4 (6), E1000092 (2008) :
Dang, J., et al. Mol. Cell. Biol. 21(17):5935-5945(2001)
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