|Application ||WB, E|
|Other Accession||NP_001157781.1, NP_060825.2|
|Calculated MW||68798 Da|
|Antigen Region||155-184 aa|
|Other Names||Zinc finger protein 415, ZNF415|
|Target/Specificity||This ZNF415 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-184 amino acids from the N-terminal region of human ZNF415.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF415 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in transcriptional regulation. Transcriptional activity differed among the various isoforms. All isoforms except isoform 3 seem to suppresses the transcriptional activities of AP- 1 and p53/TP53.|
|Cellular Location||Nucleus. Cytoplasm. Note=Isoforms 1, isoform 2, isoform 4 and isoform 5 showed both nuclear and cytoplasm localization. Isoform 3 localized only to nucleus|
|Tissue Location||Expressed in all tissues examined. Isoforms are differentially expressed. Isoform 3 and isoform 5 were highly expressed, isoform 4 moderately expressed, isoform 2 lower expression, the lowest expression level was seem with isoform 1|
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Provided below are standard protocols that you may find useful for product applications.
ZNF415 is involved in transcriptional regulation. Transcriptional activity differed among the various isoforms. All isoforms except isoform 3 seem to suppresses the transcriptional activities of AP-1 and TP53/p53.
Cheng, Y., et al. Biochem. Biophys. Res. Commun. 351(1):33-39(2006)
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