|Application ||WB, IHC-P, E|
|Calculated MW||51996 Da|
|Antigen Region||376-405 aa|
|Other Names||Flt3-interacting zinc finger protein 1, Zinc finger protein 798, FIZ1, ZNF798|
|Target/Specificity||This FIZ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-405 amino acids from the C-terminal region of human FIZ1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FIZ1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation (By similarity).|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina.
Mali, R.S., et al. Exp. Eye Res. 84(2):349-360(2007)
Mitton, K.P., et al. Hum. Mol. Genet. 12(4):365-373(2003)
Wolf, I., et al. J. Biol. Chem. 274(30):21478-21484(1999)
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