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CASS4 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP13515b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP13515b-ev20 Ev20 size 100 ul In Stock $ 95.00 Add to cart
  • Specification
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CASS4 Antibody (C-term) - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ9NQ75
Other AccessionNP_001157588.1, NP_001157587.1, NP_001157586.1, NP_065089.2
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW87144 Da

CASS4 Antibody (C-term) - Additional info

Gene ID 57091
Other Names
CASS4; C20orf32; HEFL; Cas scaffolding protein family member 4; HEF-like protein; HEF1-EFS-p130Cas-like protein
Target/Specificity
This CASS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 609-639 amino acids from the C-terminal region of human CASS4.
Dilution
WB~~1:100~500
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
CASS4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

CASS4 Antibody (C-term) - Protein Information

Name CASS4
Synonyms C20orf32, HEFL
Function
Docking protein that plays a role in tyrosine kinase- based signaling related to cell adhesion and cell spreading Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading
Cellular Location
Cytoplasm, cytoskeleton. Cell junction, focal adhesion
Tissue Location
Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines

CASS4 Antibody (C-term) - Related products

AP13515b: CASS4 Antibody (C-term)

CASS4 Antibody (C-term) - Application data

  • CASS4 Antibody (C-term) (Cat. #AP13515b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CASS4 antibody detected the CASS4 protein (arrow).

CASS4 Antibody (C-term) - Research Areas

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BACKGROUND

Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.

REFERENCES

Singh, M.K., et al. Mol. Biol. Cell 19(4):1627-1636(2008) Rikova, K., et al. Cell 131(6):1190-1203(2007) Deloukas, P., et al. Nature 414(6866):865-871(2001)