DNAL4 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | O96015 |
Other Accession | A4F4L4, Q32KN5, NP_005731.1 |
Reactivity | Human |
Predicted | Bovine, Pig |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 12009 Da |
Antigen Region | 1-30 aa |
Gene ID | 10126 |
---|---|
Other Names | Dynein light chain 4, axonemal, DNAL4 |
Target/Specificity | This DNAL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DNAL4. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DNAL4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DNAL4 |
---|---|
Function | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme |
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Provided below are standard protocols that you may find useful for product applications.
Background
DNAL4 is a component of the dynein motor complex (Iwasaki et al., 2005 [PubMed 15454493]).
References
Iwasaki, M., et al. Blood 105(2):784-793(2005)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Collins, J.E., et al. Genome Res. 13(1):27-36(2003)
Yano, H., et al. J. Neurosci. 21 (3), RC125 (2001) :
Dunham, I., et al. Nature 402(6761):489-495(1999)
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