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CHSY1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CHSY1 Antibody (Center) AP13586c
    CHSY1 Antibody (Center) (Cat. #AP13586c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CHSY1 antibody detected the CHSY1 protein (arrow).
  • WB - CHSY1 Antibody (Center) AP13586c
    CHSY1 Antibody (Center) (Cat. #AP13586c) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CHSY1 antibody detected the CHSY1 protein (arrow).
  • FC - CHSY1 Antibody (Center) AP13586c
    CHSY1 Antibody (Center) (Cat. #AP13586c) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86X52
Other Accession NP_055733.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 91784 Da
Antigen Region 504-533 aa
Additional Information
Gene ID 22856
Other Names Chondroitin sulfate synthase 1, Chondroitin glucuronyltransferase 1, Chondroitin synthase 1, ChSy-1, Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1, N-acetylgalactosaminyltransferase 1, CHSY1, CHSY, CSS1, KIAA0990
Target/Specificity This CHSY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 504-533 amino acids from the Central region of human CHSY1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCHSY1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CHSY1
Synonyms CHSY, CSS1, KIAA0990
Function Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
Cellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein Secreted
Tissue Location Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes.
Citations (0)

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CHSY1 synthesizes chondroitin sulfate, a glycosaminoglycan expressed on the surface of most cells and in extracellular matrices. Glycosaminoglycan chains are covalently linked to a wide range of core protein families and regulate many biologic processes, including cell proliferation and recognition, extracellular matrix deposition, and morphogenesis.[supplied by OMIM].


Yada, T., et al. J. Biol. Chem. 278(41):39711-39725(2003)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Kitagawa, H., et al. J. Biol. Chem. 278(26):23666-23671(2003)
Kitagawa, H., et al. J. Biol. Chem. 276(42):38721-38726(2001)

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$ 295.00
$ 99.00
Cat# AP13586c
(40 western blots)
Availability: In Stock
Bulk Size
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