|Application ||IHC-P, WB, E|
|Other Accession||NP_001005498.2, NP_078875.4|
|Calculated MW||96686 Da|
|Antigen Region||80-109 aa|
|Other Names||Inactive rhomboid protein 2, iRhom2, Rhomboid 5 homolog 2, Rhomboid family member 2, Rhomboid veinlet-like protein 5, Rhomboid veinlet-like protein 6, RHBDF2, IRHOM2, RHBDL5, RHBDL6|
|Target/Specificity||This RHBDF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids from the N-terminal region of human RHBDF2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RHBDF2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||IRHOM2, RHBDL5, RHBDL6|
|Function||Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane|
|Tissue Location||Found in the epidermis and esophageal epithelium.|
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Not expected to have protease activity (By similarity).
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