CORO2A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q92828 |
Other Accession | NP_438171.1, NP_003380.3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 59763 Da |
Antigen Region | 185-213 aa |
Gene ID | 7464 |
---|---|
Other Names | Coronin-2A, IR10, WD repeat-containing protein 2, CORO2A, IR10, WDR2 |
Target/Specificity | This CORO2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the Central region of human CORO2A. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CORO2A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CORO2A |
---|---|
Synonyms | IR10, WDR2 |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
References
Jin, Y., et al. Nat. Genet. 42(7):576-578(2010)
Marshall, T.W., et al. J. Cell. Sci. 122 (PT 17), 3061-3069 (2009) :
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Yoon, H.G., et al. Mol. Cell 12(3):723-734(2003)
Yoon, H.G., et al. EMBO J. 22(6):1336-1346(2003)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.