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LIMS2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LIMS2 Antibody (C-term) AP13597b
    LIMS2 Antibody (C-term) (Cat. #AP13597b) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the LIMS2 antibody detected the LIMS2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q7Z4I7
Other Accession NP_001154875.1, NP_060450.2, NP_001129509.2, NP_001154876.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 38916 Da
Antigen Region 309-337 aa
Additional Information
Gene ID 55679
Other Names LIM and senescent cell antigen-like-containing domain protein 2, LIM-like protein 2, Particularly interesting new Cys-His protein 2, PINCH-2, LIMS2, PINCH2
Target/Specificity This LIMS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human LIMS2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLIMS2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LIMS2
Synonyms PINCH2
Function Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration.
Cellular Location Nucleus. Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side
Research Areas
Citations (0)
citation

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Background

LIMS2 is a focal adhesion protein that associates with integrin-linked kinase (ILK; MIM 602366), a multidomain protein that mediates multiple protein-protein interactions at adhesion sites between cells and the extracellular matrix (ECM).[supplied by OMIM].

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Kim, S.K., et al. Biochem. Biophys. Res. Commun. 349(3):1032-1040(2006)
Zhang, Y., et al. J. Biol. Chem. 277(41):38328-38338(2002)
Tu, Y., et al. J. Cell Biol. 153(3):585-598(2001)

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$ 365.00
$ 140.00
Cat# AP13597b
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