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SAMD4B Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q5PRF9 |
| Other Accession | NP_060498.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 75483 Da |
| Antigen Region | 414-442 aa |
| Gene ID | 55095 |
|---|---|
| Other Names | Protein Smaug homolog 2, Smaug 2, hSmaug2, Sterile alpha motif domain-containing protein 4B, SAM domain-containing protein 4B, SAMD4B, SMAUG2 |
| Target/Specificity | This SAMD4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the C-terminal region of human SAMD4B. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SAMD4B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SAMD4B |
|---|---|
| Synonyms | SMAUG2 |
| Function | Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A. |
| Cellular Location | Cytoplasm. Nucleus |
| Tissue Location | Widely expressed in embryonic and adult tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Sterile alpha motif is a widespread domain in signalling and nuclear proteins. In EPH-related tyrosine kinases, it appears to mediate cell-cell initiated signal transduction via the binding of SH2-containing proteins to a conserved tyrosine. SAMD4B (Sterile alpha motif domain-containing protein 4B) belongs to the SMAUG family. SAMD4B contains 1 SAM (sterile alpha motif) domain.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :
Luo, N., et al. BMB Rep 43(5):355-361(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
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