|Application ||WB, IHC-P, E|
|Other Accession||P07825, Q62277, NP_003170.1|
|Calculated MW||33845 Da|
|Antigen Region||225-253 aa|
|Other Names||Synaptophysin, Major synaptic vesicle protein p38, SYP|
|Target/Specificity||This SYP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the C-terminal region of human SYP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SYP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome|
|Tissue Location||Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype|
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Provided below are standard protocols that you may find useful for product applications.
Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.[supplied by OMIM].
Ishida, M., et al. Oncol. Rep. 22(4):733-737(2009)
Sterlacci, W., et al. Virchows Arch. 455(2):125-132(2009)
Head, E., et al. Neurobiol. Aging 30(7):1125-1134(2009)
Gulubova, M., et al. J. Gastroenterol. Hepatol. 23(10):1574-1585(2008)
Glantz, L.A., et al. Neuroscience 149(3):582-591(2007)
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