SYP Antibody (C-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, E |
---|---|
Primary Accession | P08247 |
Other Accession | P07825, Q62277, NP_003170.1 |
Reactivity | Human, Mouse |
Predicted | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit Ig |
Calculated MW | 33845 Da |
Antigen Region | 225-253 aa |
Gene ID | 6855 |
---|---|
Other Names | Synaptophysin, Major synaptic vesicle protein p38, SYP |
Target/Specificity | This SYP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the C-terminal region of human SYP. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SYP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SYP |
---|---|
Function | Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). |
Cellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome |
Tissue Location | Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype |

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Provided below are standard protocols that you may find useful for product applications.
Background
Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.[supplied by OMIM].
References
Ishida, M., et al. Oncol. Rep. 22(4):733-737(2009)
Sterlacci, W., et al. Virchows Arch. 455(2):125-132(2009)
Head, E., et al. Neurobiol. Aging 30(7):1125-1134(2009)
Gulubova, M., et al. J. Gastroenterol. Hepatol. 23(10):1574-1585(2008)
Glantz, L.A., et al. Neuroscience 149(3):582-591(2007)

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