|Application ||WB, IHC-P, E|
|Calculated MW||198561 Da|
|Antigen Region||1338-1367 aa|
|Other Names||Xin actin-binding repeat-containing protein 1, Cardiomyopathy-associated protein 1, XIRP1, CMYA1, XIN|
|Target/Specificity||This XIRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1338-1367 amino acids from the C-terminal region of human XIRP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||XIRP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protects actin filaments from depolymerization.|
|Cellular Location||Cell junction. Note=Colocalizes with actin stress fibers|
|Tissue Location||Isoform A, isoform B and isoform C are expressed in heart.|
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Provided below are standard protocols that you may find useful for product applications.
XIRP1 protects actin filaments from depolymerization.
Claeys, K.G., et al. Acta Neuropathol. 117(3):293-307(2009)
van der Ven, P.F., et al. Exp. Cell Res. 312(11):2154-2167(2006)
Pacholsky, D., et al. J. Cell. Sci. 117 (PT 22), 5257-5268 (2004) :
Sinn, H.W., et al. Dev. Dyn. 225(1):1-13(2002)
Wang, D.Z., et al. Development 126(6):1281-1294(1999)
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