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XIRP1 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - XIRP1 Antibody (C-term) AP13612b
    XIRP1 Antibody (C-term) (Cat. #AP13612b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the XIRP1 antibody detected the XIRP1 protein (arrow).
    detail
  • IHC-P - XIRP1 Antibody (C-term) AP13612b
    XIRP1 Antibody (C-term) (Cat. #AP13612b)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of XIRP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q702N8
Other Accession NP_919269.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 198561 Da
Antigen Region 1338-1367 aa
Additional Information
Gene ID 165904
Other Names Xin actin-binding repeat-containing protein 1, Cardiomyopathy-associated protein 1, XIRP1, CMYA1, XIN
Target/Specificity This XIRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1338-1367 amino acids from the C-terminal region of human XIRP1.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsXIRP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name XIRP1
Synonyms CMYA1, XIN
Function Protects actin filaments from depolymerization.
Cellular Location Cell junction. Note=Colocalizes with actin stress fibers
Tissue Location Isoform A, isoform B and isoform C are expressed in heart.
Research Areas
Citations (0)
citation

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Background

XIRP1 protects actin filaments from depolymerization.

References

Claeys, K.G., et al. Acta Neuropathol. 117(3):293-307(2009)
van der Ven, P.F., et al. Exp. Cell Res. 312(11):2154-2167(2006)
Pacholsky, D., et al. J. Cell. Sci. 117 (PT 22), 5257-5268 (2004) :
Sinn, H.W., et al. Dev. Dyn. 225(1):1-13(2002)
Wang, D.Z., et al. Development 126(6):1281-1294(1999)

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$ 365.00
$ 140.00
Cat# AP13612b
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