XIRP1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q702N8 |
Other Accession | NP_919269.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 198561 Da |
Antigen Region | 1338-1367 aa |
Gene ID | 165904 |
---|---|
Other Names | Xin actin-binding repeat-containing protein 1, Cardiomyopathy-associated protein 1, XIRP1, CMYA1, XIN |
Target/Specificity | This XIRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1338-1367 amino acids from the C-terminal region of human XIRP1. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | XIRP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | XIRP1 |
---|---|
Synonyms | CMYA1, XIN |
Function | Protects actin filaments from depolymerization. |
Cellular Location | Cell junction. Note=Colocalizes with actin stress fibers |
Tissue Location | Isoform A, isoform B and isoform C are expressed in heart. |
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Provided below are standard protocols that you may find useful for product applications.
Background
XIRP1 protects actin filaments from depolymerization.
References
Claeys, K.G., et al. Acta Neuropathol. 117(3):293-307(2009)
van der Ven, P.F., et al. Exp. Cell Res. 312(11):2154-2167(2006)
Pacholsky, D., et al. J. Cell. Sci. 117 (PT 22), 5257-5268 (2004) :
Sinn, H.W., et al. Dev. Dyn. 225(1):1-13(2002)
Wang, D.Z., et al. Development 126(6):1281-1294(1999)
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