ADAL Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q6DHV7 |
Other Accession | NP_001012987.1, NP_001152752.1 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 40264 Da |
Antigen Region | 317-344 aa |
Gene ID | 161823 |
---|---|
Other Names | Adenosine deaminase-like protein, 354-, ADAL |
Target/Specificity | This ADAL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-344 amino acids from the C-terminal region of human ADAL. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ADAL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADAL |
---|---|
Synonyms | ADAL1 {ECO:0000303|PubMed:21755941} |
Function | Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine (PubMed:21755941, PubMed:29884623). Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A) (PubMed:21755941, PubMed:29884623). Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro (PubMed:21755941). |
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Provided below are standard protocols that you may find useful for product applications.
Background
ADAL is a putative nucleoside deaminase. It may catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity).
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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