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ADAL Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ADAL Antibody (C-term) AP13621b
    ADAL Antibody (C-term) (Cat. #AP13621b) western blot analysis in mouse kidney,heart tissue lysates (35ug/lane).This demonstrates the ADAL antibody detected the ADAL protein (arrow).
    detail
  • IHC-P - ADAL Antibody (C-term) AP13621b
    ADAL Antibody (C-term) (Cat. #AP13621b)immunohistochemistry analysis in formalin fixed and paraffin embedded human esophagus carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ADAL Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q6DHV7
Other Accession NP_001012987.1, NP_001152752.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 40264 Da
Antigen Region 317-344 aa
Additional Information
Gene ID 161823
Other Names Adenosine deaminase-like protein, 354-, ADAL
Target/Specificity This ADAL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-344 amino acids from the C-terminal region of human ADAL.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsADAL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADAL
Synonyms ADAL1 {ECO:0000303|PubMed:21755941}
Function Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine (PubMed:21755941, PubMed:29884623). Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A) (PubMed:21755941, PubMed:29884623). Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro (PubMed:21755941).
Citations (0)
citation

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Background

ADAL is a putative nucleoside deaminase. It may catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity).

References

Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)

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$ 365.00
$ 140.00
Cat# AP13621b
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