|Application ||WB, IHC-P, E|
|Other Accession||Q9QUS6, NP_036348.2, NP_438112.2|
|Calculated MW||83210 Da|
|Antigen Region||690-717 aa|
|Other Names||Probable E3 ubiquitin-protein ligase MID2, 632-, Midin-2, Midline defect 2, Midline-2, RING finger protein 60, Tripartite motif-containing protein 1, MID2, FXY2, RNF60, TRIM1|
|Target/Specificity||This MID2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-717 amino acids from the C-terminal region of human MID2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MID2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||FXY2, RNF60, TRIM1|
|Function||May play a role in microtubule stabilization.|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated|
|Tissue Location||Low level in fetal kidney and lung, and in adult prostate, ovary and small intestine|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Lim, J., et al. Cell 125(4):801-814(2006)
Jehee, F.S., et al. Am. J. Med. Genet. A 139(3):221-226(2005)
Yap, M.W., et al. Proc. Natl. Acad. Sci. U.S.A. 101(29):10786-10791(2004)
Short, K.M., et al. BMC Cell Biol. 3, 1 (2002) :
Reymond, A., et al. EMBO J. 20(9):2140-2151(2001)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.