|Application ||WB, IHC-P, E|
|Other Accession||NP_569074.2, NP_569073.1, NP_067629.2, NP_001003827.1|
|Calculated MW||56864 Da|
|Antigen Region||67-96 aa|
|Other Names||Tripartite motif-containing protein 34, Interferon-responsive finger protein 1, RING finger protein 21, TRIM34, IFP1, RNF21|
|Target/Specificity||This TRIM34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human TRIM34.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRIM34 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function as antiviral protein and may contribute to the defense against retroviral infections.|
|Tissue Location||Isoform 1 is the most abundant form. It is highly expressed in the placenta, spleen, colon and peripheral blood leukocytes.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq].
Sawyer, S.L., et al. PLoS Pathog. 3 (12), E197 (2007) :
Li, X., et al. Virology 360(2):419-433(2007)
Zhang, F., et al. Virology 353(2):396-409(2006)
Li, X., et al. J. Virol. 80(13):6198-6206(2006)
Reymond, A., et al. EMBO J. 20(9):2140-2151(2001)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.