|Application ||WB, E|
|Other Accession||P56873, NP_006387.1|
|Calculated MW||21474 Da|
|Antigen Region||9-37 aa|
|Other Names||Sjoegren syndrome/scleroderma autoantigen 1, Autoantigen p27, SSSCA1|
|Target/Specificity||This SSSCA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human SSSCA1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SSSCA1 Antibody (N-term ) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies.|
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Provided below are standard protocols that you may find useful for product applications.
This antigen is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established.
Shen, A., et al. Neurosurgery 65(1):153-159(2009)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Suzuki, H., et al. Genome Res. 11(10):1758-1765(2001)
Muro, Y., et al. Clin. Exp. Immunol. 111(2):372-376(1998)
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