|Application ||WB, E|
|Calculated MW||148933 Da|
|Antigen Region||639-668 aa|
|Other Names||Membrane-associated phosphatidylinositol transfer protein 2, Phosphatidylinositol transfer protein, membrane-associated 2, PITPnm 2, Pyk2 N-terminal domain-interacting receptor 3, NIR-3, PITPNM2, KIAA1457, NIR3|
|Target/Specificity||This PITPNM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-668 amino acids from the Central region of human PITPNM2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PITPNM2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions.|
|Cellular Location||Endomembrane system; Peripheral membrane protein|
|Tissue Location||Highly expressed in brain, heart, ovary, testis and thymus. Detected in small intestine, prostate, pancreas, skeletal muscle, liver, colon and placenta|
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Provided below are standard protocols that you may find useful for product applications.
PITPNM2 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005 [PubMed 15627748]).
Ocaka, L., et al. Cytogenet. Genome Res. 108(4):293-302(2005)
Tomsig, J.L., et al. J. Biol. Chem. 278(12):10048-10054(2003)
Lev, S., et al. Mol. Cell. Biol. 19(3):2278-2288(1999)
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