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ABHD4 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP13670c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13670c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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ABHD4 Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | Q8TB40 |
| Other Accession | Q5EA59, NP_071343.2 |
| Reactivity | Mouse |
| Predicted | Bovine |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 38794 Da |
ABHD4 Antibody (Center) - Additional info | |
| Gene ID 63874 | |
| Other Names ABHD4; Abhydrolase domain-containing protein 4; Alpha/beta-hydrolase 4; Lyso-N-acylphosphatidylethanolamine lipase | |
| Target/Specificity This ABHD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-127 amino acids from the Central region of human ABHD4. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABHD4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABHD4 Antibody (Center) - Protein Information | |
| Name ABHD4 | |
| Function Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine (By similarity) | |
ABHD4 Antibody (Center) - Related products
ABHD4 Antibody (Center) - Application data
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ABHD4 Antibody (Center) (Cat. #AP13670c) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the ABHD4 antibody detected the ABHD4 protein (arrow).
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ABHD4 Antibody (Center) (Cat. #AP13670c)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABHD4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
ABHD4 Antibody (Center) - Research Areas
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BACKGROUND
Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine (By similarity).
REFERENCES
Simon, G.M., et al. J. Biol. Chem. 281(36):26465-26472(2006)
