|Application ||WB, IHC-P, E|
|Other Accession||Q9JIG4, NP_149992.3|
|Calculated MW||82798 Da|
|Antigen Region||549-578 aa|
|Other Names||Protein phosphatase 1 regulatory subunit 3F, R3F, PPP1R3F|
|Target/Specificity||This PPP1R3F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the C-terminal region of human PPP1R3F.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PPP1R3F Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Glycogen-targeting subunit for protein phosphatase 1 (PP1).|
|Cellular Location||Membrane; Single-pass membrane protein|
|Tissue Location||Expressed in brain, skeletal muscle and heart.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that has been identified as one of several type-1 protein phosphatase (PP1) regulatory subunits. One or two of these subunits, together with the well-conserved catalytic subunit, can form the PP1 holoenzyme, where the regulatory subunit functions to regulate substrate specificity and/or targeting to a particular cellular compartment. Alternative splicing results in multiple transcript variants.
Suttner, K., et al. J. Allergy Clin. Immunol. 125(6):1395-1399(2010)
Piton, A., et al. Mol. Psychiatry (2010) In press :
Ceulemans, H., et al. Bioessays 24(4):371-381(2002)
Schindelhauer, D., et al. Genome Res. 6(11):1056-1069(1996)
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