PPP1R3F Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q6ZSY5 |
Other Accession | Q9JIG4, NP_149992.3 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 82798 Da |
Antigen Region | 549-578 aa |
Gene ID | 89801 |
---|---|
Other Names | Protein phosphatase 1 regulatory subunit 3F, R3F, PPP1R3F |
Target/Specificity | This PPP1R3F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the C-terminal region of human PPP1R3F. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PPP1R3F Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PPP1R3F |
---|---|
Function | Glycogen-targeting subunit for protein phosphatase 1 (PP1). |
Cellular Location | Membrane; Single-pass membrane protein |
Tissue Location | Expressed in brain, skeletal muscle and heart. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein that has been identified as one of several type-1 protein phosphatase (PP1) regulatory subunits. One or two of these subunits, together with the well-conserved catalytic subunit, can form the PP1 holoenzyme, where the regulatory subunit functions to regulate substrate specificity and/or targeting to a particular cellular compartment. Alternative splicing results in multiple transcript variants.
References
Suttner, K., et al. J. Allergy Clin. Immunol. 125(6):1395-1399(2010)
Piton, A., et al. Mol. Psychiatry (2010) In press :
Ceulemans, H., et al. Bioessays 24(4):371-381(2002)
Schindelhauer, D., et al. Genome Res. 6(11):1056-1069(1996)
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