|Application ||WB, E|
|Calculated MW||23046 Da|
|Antigen Region||6-35 aa|
|Other Names||Transmembrane protein 17, TMEM17|
|Target/Specificity||This TMEM17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human TMEM17.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TMEM17 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).|
|Cellular Location||Cell projection, cilium membrane; Multi-pass membrane protein Note=Localizes to the transition zone of primary cilia|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.