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PTH Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PTH Antibody (Center) AP13695c
    PTH Antibody (Center) (Cat. #AP13695c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PTH antibody detected the PTH protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P01270
Other Accession Q9XT35, NP_000306.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 12861 Da
Antigen Region 59-88 aa
Additional Information
Gene ID 5741
Other Names Parathyroid hormone, PTH, Parathormone, Parathyrin, PTH
Target/Specificity This PTH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the Central region of human PTH.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTH Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTH
Function PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH).

References

Giroux, S., et al. Bone 47(5):975-981(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Xu, M., et al. Bone 47(2):341-352(2010)
Gardham, C., et al. Clin J Am Soc Nephrol 5(7):1261-1267(2010)
Tawfeek, H., et al. PLoS ONE 5 (8), E12290 (2010) :

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Cat# AP13695c
Size:
Quantity:
(40 western blots)
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