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HBG1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HBG1 Antibody (Center) AP13696c
    Western blot analysis of HBG1 (arrow) using rabbit polyclonal HBG1 Antibody (Center) (Cat. #AP13696c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HBG1 gene.
  • WB - HBG1 Antibody (Center) AP13696c
    HBG1 Antibody (Center) (Cat. #AP13696c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the HBG1 antibody detected the HBG1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P69891
Other Accession NP_000550.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 16140 Da
Antigen Region 56-85 aa
Additional Information
Gene ID 3047
Other Names Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain, HBG1
Target/Specificity This HBG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the Central region of human HBG1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHBG1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HBG1
Function Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
Tissue Location Red blood cells.
Research Areas
Citations (0)

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The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.


Zhou, D., et al. Nat. Genet. 42(9):742-744(2010)
Miccio, A., et al. Mol. Cell. Biol. 30(14):3460-3470(2010)
Nuinoon, M., et al. Hum. Genet. (2009) In press :
da Cunha, A.F., et al. Hemoglobin 33(6):439-447(2009)
Hamid, M., et al. Hemoglobin 33(6):428-438(2009)

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$ 295.00
$ 99.00
Cat# AP13696c
(40 western blots)
Availability: In Stock
Bulk Size
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