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STAT4 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP13722b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13722b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
STAT4 Antibody (C-term) - Product info | |
| Application | WB, IF, IHC
|
| Primary Accession | Q14765 |
| Other Accession | P42228, NP_003142.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 85941 Da |
STAT4 Antibody (C-term) - Additional info | |
| Gene ID 6775 | |
| Other Names STAT4; Signal transducer and activator of transcription 4 | |
| Target/Specificity This STAT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-695 amino acids from the C-terminal region of human STAT4. | |
| Dilution WB~~1:100~500WB~~1:1000 IF~~1:10~50 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions STAT4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
STAT4 Antibody (C-term) - Protein Information | |
| Name STAT4 | |
| Function Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling | |
| Cellular Location Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation | |
STAT4 Antibody (C-term) - Related products
AP13722b: STAT4 Antibody (C-term)
RI15111: STAT4 predesign siRNA
DC06214: Human STAT4 cDNA Clone
STAT4 Antibody (C-term) - Application data
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STAT4 Antibody (C-term) (Cat. #AP13722b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the STAT4 antibody detected the STAT4 protein (arrow).
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Confocal immunofluorescent analysis of STAT4 Antibody (C-term) (Cat#AP13722b) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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STAT4 Antibody (C-term) (Cat. #AP13722b)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STAT4 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
STAT4 Antibody (C-term) - Research Areas
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BACKGROUND
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.
REFERENCES
Plant, D., et al. Ann. Rheum. Dis. 69(8):1548-1553(2010) Gestermann, N., et al. Genes Immun. 11(5):432-438(2010) Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010) Vuong, M.T., et al. PLoS ONE 5 (5), E10559 (2010) : Glas, J., et al. PLoS ONE 5 (4), E10373 (2010) :
