STAT4 Antibody (C-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IF, IHC-P, E |
---|---|
Primary Accession | Q14765 |
Other Accession | P42228, NP_003142.1 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit Ig |
Calculated MW | 85941 Da |
Antigen Region | 666-695 aa |
Gene ID | 6775 |
---|---|
Other Names | Signal transducer and activator of transcription 4, STAT4 |
Target/Specificity | This STAT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-695 amino acids from the C-terminal region of human STAT4. |
Dilution | WB~~1:1000 IF~~1:10~50 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | STAT4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STAT4 |
---|---|
Function | Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling. |
Cellular Location | Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation |

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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.
References
Plant, D., et al. Ann. Rheum. Dis. 69(8):1548-1553(2010)
Gestermann, N., et al. Genes Immun. 11(5):432-438(2010)
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
Vuong, M.T., et al. PLoS ONE 5 (5), E10559 (2010) :
Glas, J., et al. PLoS ONE 5 (4), E10373 (2010) :

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