|Application ||WB, E|
|Calculated MW||35578 Da|
|Antigen Region||260-288 aa|
|Other Names||Low affinity immunoglobulin gamma Fc region receptor II-c, IgG Fc receptor II-c, CDw32, Fc-gamma RII-c, Fc-gamma-RIIc, FcRII-c, CD32, FCGR2C, CD32, FCG2, IGFR2|
|Target/Specificity||This FCGR2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-288 amino acids from the C-terminal region of human FCGR2C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FCGR2C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD32, FCG2, IGFR2|
|Function||Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.|
|Cellular Location||Isoform IIC4: Cytoplasm. Isoform IIC2: Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Isoform IIC1 is detected in monocytes, macrophages, polymorphonuclear cells and natural killer cells|
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Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.
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