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MMP15 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MMP15 Antibody (N-term) AP13751a
    MMP15 Antibody (N-term) (Cat. #AP13751a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MMP15 antibody detected the MMP15 protein (arrow).
  • IHC-P - MMP15 Antibody (N-term) AP13751a
    MMP15 Antibody (N-term) (AP13751a)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP15 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51511
Other Accession NP_002419.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 75807 Da
Antigen Region 168-196 aa
Additional Information
Gene ID 4324
Other Names Matrix metalloproteinase-15, MMP-15, 3424-, Membrane-type matrix metalloproteinase 2, MT-MMP 2, MTMMP2, Membrane-type-2 matrix metalloproteinase, MT2-MMP, MT2MMP, SMCP-2, MMP15
Target/Specificity This MMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the N-terminal region of human MMP15.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMMP15 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMP15
Function Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.
Cellular Location Membrane; Single-pass type I membrane protein; Extracellular side
Tissue Location Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle
Research Areas
Citations (0)

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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.


Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Nalpas, B., et al. Gut 59(8):1120-1126(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Mohammad, M.A., et al. Int. J. Biol. Markers 25(2):69-74(2010)

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$ 295.00
$ 99.00
Cat# AP13751a
(40 western blots)
Availability: In Stock
Bulk Size
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