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TRPC5 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TRPC5 Antibody (N-term) AP13769A
    TRPC5 Antibody (N-term) (Cat. #AP13769a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TRPC5 antibody detected the TRPC5 protein (arrow).
  • IHC-P - TRPC5 Antibody (N-term) AP13769A
    TRPC5 Antibody (N-term) (Cat. #AP13769a)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRPC5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UL62
Other Accession O62852, Q9QX29, NP_036603.1
Reactivity Human
Predicted Mouse, Rabbit
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 111412 Da
Antigen Region 254-283 aa
Additional Information
Gene ID 7224
Other Names Short transient receptor potential channel 5, TrpC5, Transient receptor protein 5, TRP-5, hTRP-5, hTRP5, TRPC5, TRP5
Target/Specificity This TRPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-283 amino acids from the N-terminal region of human TRPC5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTRPC5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRPC5
Synonyms TRP5
Function Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole
Research Areas
Citations (0)

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This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1).


Al-Shawaf, E., et al. Arterioscler. Thromb. Vasc. Biol. 30(7):1453-1459(2010)
Wong, C.O., et al. Pflugers Arch. 460(1):121-130(2010)
Miehe, S., et al. J. Biol. Chem. 285(16):12426-12434(2010)
Gross, S.A., et al. J. Biol. Chem. 284(49):34423-34432(2009)
Everett, K.V., et al. Hum. Genet. (2009) In press :

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$ 295.00
$ 99.00
Cat# AP13769A
(40 western blots)
Availability: In Stock
Bulk Size
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