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Mouse Cdk3 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP13803b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP13803b-ev20 Ev20 size 100 ul In Stock $ 95.00 Add to cart
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Mouse Cdk3 Antibody (C-term) - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ80YP0
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW33888 Da

Mouse Cdk3 Antibody (C-term) - Additional info

Other Names
Cdk3; Cdkn3; Cyclin-dependent kinase 3; Cell division protein kinase 3
Target/Specificity
This Mouse Cdk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 amino acids from the C-terminal region of Mouse Cdk3.
Dilution
WB~~1:100~500
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
Mouse Cdk3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

Mouse Cdk3 Antibody (C-term) - Protein Information

Name Cdk3
Synonyms Cdkn3
Function
Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0- G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1- independent manner

Mouse Cdk3 Antibody (C-term) - Related products

AP13803b: Mouse Cdk3 Antibody (C-term)

BP13803b: Mouse Cdk3 Antibody (C-term) Blocking Peptides

Mouse Cdk3 Antibody (C-term) - Application data

  • Mouse Cdk3 Antibody (C-term) (Cat. #AP13803b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the Cdk3 antibody detected the Cdk3 protein (arrow).

  • Western blot analysis of Cdk3 (arrow) using rabbit polyclonal Mouse Cdk3 Antibody (C-term) (Cat. #AP13803b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Cdk3 gene.

Mouse Cdk3 Antibody (C-term) - Research Areas

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

Probably involved in the control of the cell cycle. Interacts with a yet unknown type of cyclin. Can phosphorylate histone H1 (By similarity).