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>   home   >   Products   >   Primary Antibodies   >   Developmental Biology   >   MARCH11 Antibody (C-term)   

MARCH11 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MARCH11 Antibody (C-term) AP13811b
    MARCH11 Antibody (C-term) (Cat. #AP13811b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the 40613 antibody detected the 40613 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession A6NNE9
Other Accession A6P320, Q8CBH7, NP_001096032.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 43878 Da
Antigen Region 308-337 aa
Additional Information
Gene ID 441061
Other Names E3 ubiquitin-protein ligase MARCH11, 632-, Membrane-associated RING finger protein 11, Membrane-associated RING-CH protein XI, MARCH-XI, MARCH11
Target/Specificity This MARCH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human MARCH11.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMARCH11 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MARCH11
Function E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids (By similarity).
Cellular Location Cytoplasmic vesicle membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]).


Rose, J. Phd, et al. Mol. Med. (2010) In press :
Morokuma, Y., et al. J. Biol. Chem. 282(34):24806-24815(2007)

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$ 295.00
$ 99.00
Cat# AP13811b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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