|Application ||WB, E|
|Calculated MW||26801 Da|
|Antigen Region||1-30 aa|
|Other Names||Lysosomal-associated transmembrane protein 4A, Golgi 4-transmembrane-spanning transporter MTP, LAPTM4A, KIAA0108, LAPTM4, MBNT, MTRP|
|Target/Specificity||This LAPTM4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LAPTM4A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LAPTM4A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA0108, LAPTM4, MBNT, MTRP|
|Function||May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.|
|Cellular Location||Endomembrane system; Multi- pass membrane protein. Note=May reside in an intracellular membrane-bound compartment.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that has four predicted transmembrane domains. The function of this gene has not yet been determined; however, studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes.
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Tomarev, S.I., et al. Invest. Ophthalmol. Vis. Sci. 44(6):2588-2596(2003)
Hoja, M.R., et al. Exp. Cell Res. 259(1):239-246(2000)
Hogue, D.L., et al. J. Biol. Chem. 271(16):9801-9808(1996)
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