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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   LY6E Antibody (Center)   

LY6E Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LY6E Antibody (Center) AP13818c
    LY6E Antibody (Center) (Cat. #AP13818c) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the LY6E antibody detected the LY6E protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16553
Other Accession NP_002337.1, NP_001120685.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 13507 Da
Antigen Region 41-70 aa
Additional Information
Gene ID 4061
Other Names Lymphocyte antigen 6E, Ly-6E, Retinoic acid-induced gene E protein, RIG-E, Stem cell antigen 2, SCA-2, Thymic shared antigen 1, TSA-1, LY6E, RIGE, SCA2, TSA1
Target/Specificity This LY6E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the Central region of human LY6E.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLY6E Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LY6E
Synonyms 9804, RIGE, SCA2, TSA1
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor
Tissue Location Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes
Research Areas
Citations (0)

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Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. In the periphery, Sca1 exhibits a pattern of expression which is based on differences between the two allotypes. Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1+ resting peripheral lymphocytes, whereas Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1+ lymphocytes. The expression of Sca1 is dramatically upregulated in all strains upon cellular activation.


Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Wang, J.L., et al. Mov. Disord. 24(13):2007-2011(2009)
Socal, M.P., et al. Parkinsonism Relat. Disord. 15(5):374-378(2009)
Tang, J., et al. Lupus 17(9):805-813(2008)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)

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Cat# AP13818c
(40 western blots)
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