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TMTC4 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q5T4D3 |
| Other Accession | NP_001073137.1, NP_116202.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 82991 Da |
| Antigen Region | 175-204 aa |
| Gene ID | 84899 |
|---|---|
| Other Names | Transmembrane and TPR repeat-containing protein 4, TMTC4 |
| Target/Specificity | This TMTC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-204 amino acids from the N-terminal region of human TMTC4. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TMTC4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TMTC4 (HGNC:25904) |
|---|---|
| Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O- mannosyl-transferase on other proteins such as PDIA3. |
| Cellular Location | Membrane; Multi-pass membrane protein. Endoplasmic reticulum |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
TMTC4 belongs to the TMTC family. Its exact function remains unknown.
References
Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
Rual, J.F., et al. Genome Res. 14 (10B), 2128-2135 (2004) :
Dunham, A., et al. Nature 428(6982):522-528(2004)
Christian, S.L., et al. Genomics 79(5):635-656(2002)
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